Incubator-independent cell-culture perfusion platform for continuous long-termmicroelectrode array electrophysiology and time-lapse imaging
Konduri, Anil Krishna
MetadataShow full item record
Mostin vitro electrophysiology studies extract information and draw conclusions from representative, temporally limited snapshot experiments. This approach bears the risk of missing decisive moments that may make a difference in our understanding of physiological events. This feasibility study presents a simple benchtop cell-culture perfusion system adapted to commercial microelectrode arrays (MEAs), multichannel electrophysiology equipment and common inverted microscopy stages for simultaneous and uninterrupted extracellular electrophysiology and time-lapse imaging at ambient CO2 levels.
- Education